Non-Mammalian cDNA
Abcam GR 55562 dihydrochloride, 5-HT1B / 5-HT1D receptor antagonist, 50MG
MW 448.4 Da, Purity >99%. Selective, competitive 5-HT1B/ 5-HT1D receptor antagonist (pKi values are 7.4 and 6.2, respectively). Inhibits 5-HT evoked contraction in pulmonary resistance arteries (pEC10 = 7.26).
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Anatabine dicitrate | 99.03% | 544.46 | 50 MG
Anatabine dicitrate is a tobacco alkaloid capable of crossing the blood-brain barrier. It acts as a potent α4β2 nAChR agonist. This compound inhibits NF-κB activation, which leads to a reduction in amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Additionally, Anatabine dicitrate demonstrates anti-inflammatory effects and shows potential for the treatment of neurodegenerative disorders.
- Can cross the blood-brain barrier.
- Potent α4β2 nAChR agonist.
- Inhibits NF-κB activation.
- Lowers amyloid-β (Aβ) production by preventing the β-cleavage of APP.
- Possesses anti-inflammatory effects.
- Has potential for neurodegenerative disorders treatment.
Cayman Chemical BryostatIn 1 10ug
A marine macrolide with diverse biological activities; binds to PKCα, PKCβ1, PKCγ, PKCδ, PKCε, PKCη, and PKCθ (Kis = 0.8-3.0 nM); induces PKC activation or inhibition in cancer cells in a concentration-dependent manner; reduces the production of IL-2 and increases the production of IL-10 in LPS-stimulated mouse BMDCs at 50 nM; decreases cell surface levels of CD4 and CCR5 and reduces HIV-1 infectivity in isolated human monocyte-derived macrophages; reduces spinal cord and brain T cell infiltration and disease severity in a mouse model of EAE at 30 UG/kg; decreases blast-induced increases in BBB permeability in a rat model of TBI at 2.5 mg/kg
ABclonal Technology SLC18A3 Rabbit pAb
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
ABclonal Technology SLC18A3 Rabbit pAb
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
OriGene CD153 (TNFSF8) (NM_001244) Human Mass Spec Standard, 10ug
TNFSF8 MS Standard C13 and N15-labeled recombinant protein (NP_001235)